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1

Adolescent d-amphetamine treatment in a rodent model of ADHD: Pro-cognitive effects during adolescence and cocaine abuse risk during adulthood

Jordan, Chloe J., Taylor, Danielle M., Jeon, Sae-Mi, Baskin, Britahny M., Dwoskin, Linda P., Kantak, Kathleen M.

Journal:

Drug and Alcohol Dependence

Year:

2015

Language:

english

File:

PDF, 57 KB

english, 2015

2

Review of the Pharmacology and Clinical Profile of Bupropion, an Antidepressant and Tobacco Use Cessation Agent

Linda P. Dwoskin, Anthony S. Rauhut, Kelley A. King-Pospisil, Michael T. Bardo

Journal:

CNS Drug Reviews

Year:

2006

Language:

english

File:

PDF, 184 KB

english, 2006

3

Lobelane decreases methamphetamine self-administration in rats

Nichole M. Neugebauer, Steven B. Harrod, Dustin J. Stairs, Peter A. Crooks, Linda P. Dwoskin, Michael T. Bardo

Journal:

European Journal of Pharmacology

Year:

2007

Language:

english

File:

PDF, 250 KB

english, 2007

4

ChemInform Abstract: Quinlobelane: A Water-Soluble Lobelane Analogue and Inhibitor of VMAT2.

Ashish P. Vartak, A. Gabriela Deaciuc, Linda P. Dwoskin, Peter A. Crooks

Journal:

Year:

2010

Language:

english

File:

PDF, 38 KB

english, 2010

5

Novel bis-2,2,6,6-tetramethylpiperidine (bis-TMP) and bis-mecamylamine antagonists at neuronal nicotinic receptors mediating nicotine-evoked dopamine release

Zhenfa Zhang, Marharyta Pivavarchyk, Karunai Leela Subramanian, A. Gabriela Deaciuc, Linda P. Dwoskin, Peter A. Crooks

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2010

Language:

english

File:

PDF, 455 KB

english, 2010

6

Expeditious synthesis of cis-1-methyl-2,3,3a,4,5,9b-hexahydro-1H-pyrrolo-[3,2h]isoquinoline/[2,3-f]quinoline via azomethine ylide-alkene [3+2] cycloaddition

Zhenfa Zhang, Linda P. Dwoskin, Peter A. Crooks

Journal:

Tetrahedron Letters

Year:

2011

Language:

english

File:

PDF, 284 KB

english, 2011

7

Development of a Novel Class of Subtype-Selective Nicotinic Receptor Antagonist: Pyridine-N-Substituted Nicotine Analogs

LINDA P. DWOSKIN, LINCOLN H. WILKINS, JAMES R. PAULY, PETER A. CROOKS

Journal:

Annals of the New York Academy of Sciences

Year:

1999

Language:

english

File:

PDF, 105 KB

english, 1999

8

Prefrontal cortex and drug abuse vulnerability: Translation to prevention and treatment interventions

Jennifer L. Perry, Jane E. Joseph, Yang Jiang, Rick S. Zimmerman, Thomas H. Kelly, Mahesh Darna, Peter Huettl, Linda P. Dwoskin, Michael T. Bardo

Journal:

Brain Research Reviews

Year:

2011

Language:

english

File:

PDF, 869 KB

english, 2011

9

Decreased norepinephrine transporter function in the orbitofrontal cortex and enhanced cocaine abuse risk following adolescent methylphenidate treatment in a rat model of Attention Deficit Hyperactivity Disorder

Somkuwar, Sucharita S., Kantak, Kathleen, Dwoskin, Linda P.

Journal:

Drug and Alcohol Dependence

Year:

2015

Language:

english

File:

PDF, 58 KB

english, 2015

10

Methylphenidate treatment beyond adolescence maintains increased cocaine self-administration in the spontaneously hypertensive rat model of attention deficit/hyperactivity disorder

Baskin, Britahny M., Dwoskin, Linda P., Kantak, Kathleen M.

Journal:

Pharmacology Biochemistry and Behavior

Year:

2015

Language:

english

File:

PDF, 634 KB

english, 2015

11

Methylphenidate Treatment in Adolescent Rats with an Attention Deficit/Hyperactivity Disorder Phenotype: Cocaine Addiction Vulnerability and Dopamine Transporter Function

Harvey, Roxann C, Sen, Sucharita, Deaciuc, Agripina, Dwoskin, Linda P, Kantak, Kathleen M

Journal:

Neuropsychopharmacology

Year:

2011

Language:

english

File:

PDF, 532 KB

english, 2011

12

Adolescent d-amphetamine treatment in a rodent model of ADHD: Pro-cognitive effects in adolescence without an impact on cocaine cue reactivity in adulthood

Jordan, Chloe J., Taylor, Danielle M., Dwoskin, Linda P., Kantak, Kathleen M.

Journal:

Behavioural Brain Research

Year:

2016

Language:

english

File:

PDF, 2.45 MB

english, 2016

13

Necessity for research directed at stimulant type and treatment-onset age to access the impact of medication on drug abuse vulnerability in teenagers with ADHD

Kantak, Kathleen M., Dwoskin, Linda P.

Journal:

Pharmacology Biochemistry and Behavior

Year:

2016

Language:

english

File:

PDF, 232 KB

english, 2016

14

Adolescent d-amphetamine treatment in a rodent model of attention deficit/hyperactivity disorder: impact on cocaine abuse vulnerability in adulthood

Jordan, Chloe J., Lemay, Carley, Dwoskin, Linda P., Kantak, Kathleen M.

Journal:

Psychopharmacology

Year:

2016

Language:

english

File:

PDF, 597 KB

english, 2016

15

The Preparation of 2-Arylmethylidene-8-methyl-8-azabicyclo[3.2.1]octan-3-ones.

Guangrong Zheng, Linda P. Dwoskin, Peter A. Crooks

Journal:

Year:

2004

File:

PDF, 18 KB

2004

16

ChemInform Abstract: Discovery of Non-Peptide, Small Molecule Antagonists of α9α10 Nicotinic Acetylcholine Receptors as Novel Analgesics for the Treatment of Neuropathic and Tonic Inflammatory Pain.

Guangrong Zheng, Zhenfa Zhang, Cheryl Dowell, Elzbieta Wala, Linda P. Dwoskin, Joseph R. Holtman, J. Michael McIntosh, Peter A. Crooks

Journal:

Year:

2011

Language:

english

File:

PDF, 25 KB

english, 2011

17

ChemInform Abstract: Design, Synthesis and Interaction at the Vesicular Monoamine Transporter-2 of Lobeline Analogues: Potential Pharmacotherapies for the Treatment of Psychostimulant Abuse

Peter A. Crooks, Guangrong Zheng, Ashish P. Vartak, John P. Culver, Fang Zheng, David B. Horton, Linda P. Dwoskin

Journal:

Year:

2011

File:

PDF, 18 KB

2011

18

Synthesis and evaluation of conformationally restricted pyridino N-alkylated nicotine analogs as nicotinic acetylcholine receptor antagonists

Rui Xu, Linda P. Dwoskin, Vladimir Grinevich, Sangeetha P. Sumithran, Peter A. Crooks

Journal:

Drug Development Research

Year:

2002

Language:

english

File:

PDF, 257 KB

english, 2002

19

Inhibition of nicotine-evoked [3H] dopamine release by pyridino N-substituted nicotine analogues: A new class of nicotinic antagonist

Peter A. Crooks, Alain Ravard, Lincoln H. Wilkins, Li-Hong Teng, Susan T. Buxton, Linda P. Dwoskin

Journal:

Drug Development Research

Year:

1995

Language:

english

File:

PDF, 1.13 MB

english, 1995

20

Outflow and overflow of picogram levels of endogenous dopamine and DOPAC from rat striatal slices: improved methodology for studies of stimulus-evoked release and metabolism

Greg A. Gerhardt, Linda P. Dwoskin, Nancy R. Zahniser

Journal:

Journal of Neuroscience Methods

Year:

1989

Language:

english

File:

PDF, 806 KB

english, 1989

21

3D-QSAR study of bis-azaaromatic quaternary ammonium analogs at the blood–brain barrier choline transporter

Werner J. Geldenhuys, Paul R. Lockman, Tiffany H. Nguyen, Cornelis J. Van der Schyf, Peter A. Crooks, Linda P. Dwoskin, David D. Allen

Journal:

Bioorganic & Medicinal Chemistry

Year:

2005

Language:

english

File:

PDF, 494 KB

english, 2005

22

Lobelane analogues as novel ligands for the vesicular monoamine transporter-2

Guangrong Zheng, Linda P. Dwoskin, Agripina G. Deaciuc, Jun Zhu, Marlon D. Jones, Peter A. Crooks

Journal:

Bioorganic & Medicinal Chemistry

Year:

2005

Language:

english

File:

PDF, 311 KB

english, 2005

23

QSAR modeling of mono- and bis-quaternary ammonium salts that act as antagonists at neuronal nicotinic acetylcholine receptors mediating dopamine release

Fang Zheng, Ersin Bayram, Sangeetha P. Sumithran, Joshua T. Ayers, Chang-Guo Zhan, Jeffrey D. Schmitt, Linda P. Dwoskin, Peter A. Crooks

Journal:

Bioorganic & Medicinal Chemistry

Year:

2006

Language:

english

File:

PDF, 738 KB

english, 2006

24

Des-keto lobeline analogs with increased potency and selectivity at dopamine and serotonin transporters

Guangrong Zheng, David B. Horton, Agripina G. Deaciuc, Linda P. Dwoskin, Peter A. Crooks

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2006

Language:

english

File:

PDF, 147 KB

english, 2006

25

tris-Azaaromatic quaternary ammonium salts: Novel templates as antagonists at nicotinic receptors mediating nicotine-evoked dopamine release

Guangrong Zheng, Sangeetha P. Sumithran, Agripina G. Deaciuc, Linda P. Dwoskin, Peter A. Crooks

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2007

Language:

english

File:

PDF, 176 KB

english, 2007

26

Bis-azaaromatic quaternary ammonium salts as antagonists at nicotinic receptors mediating nicotine-evoked dopamine release: An investigation of binding conformation

Guangrong Zheng, Zhenfa Zhang, Marharyta Pivavarchyk, Agripina G. Deaciuc, Linda P. Dwoskin, Peter A. Crooks

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2007

Language:

english

File:

PDF, 166 KB

english, 2007

27

bis-Pyridinium cyclophanes: Novel ligands with high affinity for the blood–brain barrier choline transporter

Zhenfa Zhang, Paul R. Lockman, Rajendar K. Mittapalli, David D. Allen, Linda P. Dwoskin, Peter A. Crooks

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2008

Language:

english

File:

PDF, 170 KB

english, 2008

28

Tetrakis-azaaromatic quaternary ammonium salts: Novel subtype-selective antagonists at neuronal nicotinic receptors that mediate nicotine-evoked dopamine release

Zhenfa Zhang, Guangrong Zheng, Marharyta Pivavarchyk, A.Gabriela Deaciuc, Linda P. Dwoskin, Peter A. Crooks

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2008

Language:

english

File:

PDF, 888 KB

english, 2008

29

QSAR study on maximal inhibition (Imax) of quaternary ammonium antagonists for S-(−)-nicotine-evoked dopamine release from dopaminergic nerve terminals in rat striatum

Fang Zheng, Matthew J. McConnell, Chang-Guo Zhan, Linda P. Dwoskin, Peter A. Crooks

Journal:

Bioorganic & Medicinal Chemistry

Year:

2009

Language:

english

File:

PDF, 851 KB

english, 2009

30

Lobeline esters as novel ligands for neuronal nicotinic acetylcholine receptors and neurotransmitter transporters

Marhaba Hojahmat, David B. Horton, Seth D. Norrholm, Dennis K. Miller, Vladimir P. Grinevich, Agripina Gabriela Deaciuc, Linda P. Dwoskin, Peter A. Crooks

Journal:

Bioorganic & Medicinal Chemistry

Year:

2010

Language:

english

File:

PDF, 505 KB

english, 2010

31

Subtype-selective nicotinic receptor antagonists: potential as tobacco use cessation agents

Linda P Dwoskin, Sangeetha P Sumithran, Jun Zhu, A.Gabriela Deaciuc, Joshua T Ayers, Peter A Crooks

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2004

Language:

english

File:

PDF, 155 KB

english, 2004

32

Development of subtype-selective ligands as antagonists at nicotinic receptors mediating nicotine-evoked dopamine release

Peter A Crooks, Joshua T Ayers, Rui Xu, Sangeetha P Sumithran, Vladimir P Grinevich, Lincoln H Wilkins, A.Gabriela Deaciuc, David D Allen, Linda P Dwoskin

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2004

Language:

english

File:

PDF, 204 KB

english, 2004

33

Synthesis and evaluation of a series of homologues of lobelane at the vesicular monoamine transporter-2

Guangrong Zheng, Linda P. Dwoskin, Agripina G. Deaciuc, Peter A. Crooks

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2008

Language:

english

File:

PDF, 286 KB

english, 2008

34

Predictive screening model for potential vector-mediated transport of cationic substrates at the blood–brain barrier choline transporter

Werner J. Geldenhuys, Vamshi K. Manda, Rajendar K. Mittapalli, Cornelis J. Van der Schyf, Peter A. Crooks, Linda P. Dwoskin, David D. Allen, Paul R. Lockman

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2010

Language:

english

File:

PDF, 1.78 MB

english, 2010

35

Bis-azaaromatic quaternary ammonium salts as ligands for the blood–brain barrier choline transporter

Guangrong Zheng, Zhenfa Zhang, Paul R. Lockman, Werner J. Geldenhuys, David D. Allen, Linda P. Dwoskin, Peter A. Crooks

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2010

Language:

english

File:

PDF, 212 KB

english, 2010

36

Quinlobelane: A water-soluble lobelane analogue and inhibitor of VMAT2

Ashish P. Vartak, A. Gabriela Deaciuc, Linda P. Dwoskin, Peter A. Crooks

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2010

Language:

english

File:

PDF, 340 KB

english, 2010

37

Novel bis-, tris-, and tetrakis-tertiary amino analogs as antagonists at neuronal nicotinic receptors that mediate nicotine-evoked dopamine release

Zhenfa Zhang, Guangrong Zheng, Marharyta Pivavarchyk, A. Gabriela Deaciuc, Linda P. Dwoskin, Peter A. Crooks

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2011

Language:

english

File:

PDF, 746 KB

english, 2011

38

Discovery of non-peptide, small molecule antagonists of α9α10 nicotinic acetylcholine receptors as novel analgesics for the treatment of neuropathic and tonic inflammatory pain

Guangrong Zheng, Zhenfa Zhang, Cheryl Dowell, Elzbieta Wala, Linda P. Dwoskin, Joseph R. Holtman, J. Michael McIntosh, Peter A. Crooks

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2011

Language:

english

File:

PDF, 346 KB

english, 2011

39

Synthesis of symmetrical 1,5-disubstituted granatanines

Ashish P. Vartak, Linda P. Dwoskin, Peter A. Crooks

Journal:

Tetrahedron Letters

Year:

2008

Language:

english

File:

PDF, 178 KB

english, 2008

40

A simple high performance liquid chromatographic method for the quantification of total cotinine, total 3′-hydroxycotinine and caffeine in the plasma of smokers

Omar A Ghosheh, Debra Browne, Thea Rogers, José de Leon, Linda P Dwoskin, Peter A Crooks

Journal:

Journal of Pharmaceutical and Biomedical Analysis

Year:

2000

Language:

english

File:

PDF, 111 KB

english, 2000

41

Neuronal nicotinic acetylcholine receptor binding affinities of boron-containing nicotine analogues

Rui Xu, Linda P Dwoskin, Vladimir P Grinevich, Gabriela Deaciuc, Peter A Crooks

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2001

Language:

english

File:

PDF, 142 KB

english, 2001

42

N,N-Disubstituted piperazines: synthesis and affinities at α4β2∗ and α7∗ neuronal nicotinic acetylcholine receptors

Jianhong Chen, Seth Norrholm, Linda P. Dwoskin, Peter A. Crooks, Donglu Bai

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2003

Language:

english

File:

PDF, 141 KB

english, 2003

43

Lobeline Displaces [3H]Dihydrotetrabenazine Binding and Releases [3H]Dopamine from Rat Striatal Synaptic Vesicles: Comparison with d-Amphetamine

LiHong Teng, Peter A. Crooks, Linda P. Dwoskin

Journal:

Journal of Neurochemistry

Year:

1998

Language:

english

File:

PDF, 897 KB

english, 1998

44

Nornicotine inhibition of dopamine transporter function in striatum via nicotinic receptor activation

Lisa S. Middleton, Peter A. Crooks, Peter J. Wedlund, Wayne A. Cass, Linda P. Dwoskin

Journal:

Year:

2007

Language:

english

File:

PDF, 360 KB

english, 2007

45

Biphasic modulation of evoked [3H]D-aspartate release by D-2 dopamine receptors in rat striatal slices

Joanna Peris, Linda P. Dwoskin, Nancy R. Zahniser

Journal:

Year:

1988

Language:

english

File:

PDF, 837 KB

english, 1988

46

Lobeline does not serve as a reinforcer in rats

Steven B. Harrod, Linda P. Dwoskin, Thomas A. Green, Brenda J. Gehrke, Michael T. Bardo

Journal:

Psychopharmacology

Year:

2003

Language:

english

File:

PDF, 223 KB

english, 2003

47

Effect of bupropion on nicotine self-administration in rats

Anthony S. Rauhut, Nicole Neugebauer, Linda P. Dwoskin, Michael T. Bardo

Journal:

Psychopharmacology

Year:

2003

Language:

english

File:

PDF, 251 KB

english, 2003

48

The effect of a novel VMAT2 inhibitor, GZ-793A, on methamphetamine reward in rats

Joshua S. Beckmann, Emily D. Denehy, Guangrong Zheng, Peter A. Crooks, Linda P. Dwoskin, Michael T. Bardo

Journal:

Psychopharmacology

Year:

2012

Language:

english

File:

PDF, 213 KB

english, 2012

49

Once weekly administration of nicotine produces long-lasting locomotor sensitization in rats via a nicotinic receptor-mediated mechanism

Dennis K. Miller, Lincoln H. Wilkins, Michael T. Bardo, Peter A. Crooks, Linda P. Dwoskin

Journal:

Psychopharmacology

Year:

2001

Language:

english

File:

PDF, 111 KB

english, 2001

50

First-principles determination of molecular conformations of indolizidine (−)-235B′ in solution

Fang Zheng, Linda P. Dwoskin, Peter A. Crooks, Chang-Guo Zhan

Journal:

Theoretical Chemistry Accounts: Theory, Computation, and Modeling (Theoretica Chimica Acta)

Year:

2009

Language:

english

File:

PDF, 344 KB

english, 2009